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Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort

journal article hqc
Colin R Dormuth, Brandace Winquist, Anat Fisher, Fangyun Wu, Pauline Reynier, Samy Suissa, Matthew Dahl, Zhihai Ma, Xinya Lu, Jianguo Zhang, Colette B Raymond, Kristian B Filion, Robert W Platt, Carolina Moriello, J Michael Paterson, Canadian Network for Observational Drug Effect Studies (CNODES) Investigators
JAMA Network Open
April 1, 2021

The publication aims to study the association between ondansetron during pregnancy and the risks of spontaneous abortion, stillbirth, and major congenital malformations.

Citation

Dormuth CR, Winquist B, Fisher A, Wu F, Reynier P, Suissa S, Dahl M, Ma Z, Lu X, Zhang J, Raymond CB, Filion KB, Platt RW, Moriello C, Paterson JM; Canadian Network for Observational Drug Effect Studies (CNODES) Investigators. Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort. JAMA Netw Open. 2021 Apr 1;4(4):e215329. doi: 10.1001/jamanetworkopen.2021.5329. PMID: 33890993; PMCID: PMC8065380.

https://doi.org/10.1001/jamanetworkopen.2021.5329